Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50018468
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM21509(4-[2-({4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]...)
Affinity DataKi:  38nMAssay Description:Inhibition of TbetaR-1 (unknown origin) assessed as inhibition constant by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM21509(4-[2-({4-[2-(pyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-a]...)
Affinity DataKi:  300nMAssay Description:Inhibition of TbetaR-2 (unknown origin) assessed as inhibition constant by ELISA assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50608549(CHEMBL4303194)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of TbetaR-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50402166(CHEMBL2207988)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human GST tagged TGFbeta 1 using 3,3',5,5'-tetramethylbenzidine as substrate incubated for 30 mins in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50252542(3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human His-tagged TbetaR-1 assessed as inhibition of SMAD3 phosphorylation by western blot analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50608550(CHEMBL1170377)
Affinity DataIC50:  12nMAssay Description:Inhibition of TbetaR-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50320952(6-(2-tert-butyl-5-(6-methylpyridin-2-yl)-1H-imidaz...)
Affinity DataIC50:  14nMAssay Description:Inhibition of GST tagged TbetaR-1 (unknown origin) in the presence of 33 P-gamma ATPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50184872(4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-y...)
Affinity DataIC50:  18nMAssay Description:Inhibition of TbetaR-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50151347(2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...)
Affinity DataIC50:  23nMAssay Description:Inhibition of TbetaR-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50132989(4-[3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl]-quin...)
Affinity DataIC50:  25nMAssay Description:Inhibition of TbetaR-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50608551(CHEMBL1824446 | SB-505124)
Affinity DataIC50:  47nMAssay Description:Inhibition of GST tagged TbetaR-1 (unknown origin) by Westernblot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50204834(2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pterid...)
Affinity DataIC50:  48nMAssay Description:Inhibition of TbetaR-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50015640(GALUNISERTIB | LY-2157299)
Affinity DataIC50:  56nMAssay Description:Inhibition of TbetaR-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))TBA
LigandPNGBDBM50110208(4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1...)
Affinity DataIC50:  94nMAssay Description:Inhibition of TbetaR-1 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))TBA
LigandPNGBDBM50402166(CHEMBL2207988)
Affinity DataIC50:  836nMAssay Description:Inhibition of human GST tagged ALK3 incubated for 30 mins in presence of ATP by QSSA Kit methodMore data for this Ligand-Target Pair
In DepthDetails PubMed