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Found 10 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50014194
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139351(2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139355(2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139353((2-tert-Butylsulfanyl-ethyl)-dimethyl-amine | CHEM...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139361(2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine...)
Affinity DataKi:  37nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139354(1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...)
Affinity DataKi:  41nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139356(CHEMBL350166 | Dimethyl-[2-(4-pyridin-4-yl-thiazol...)
Affinity DataKi:  90nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139357(CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...)
Affinity DataKi:  210nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139360(CHEMBL161846 | [2-(Benzothiazol-2-ylsulfanyl)-ethy...)
Affinity DataKi:  830nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139363(CHEMBL162071 | Dimethyl-[2-(2-phenyl-pyridin-4-yls...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50139352(CHEMBL161203 | [2-(4-tert-Butyl-thiazol-2-ylsulfan...)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed