TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Binding affinity for Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2More data for this Ligand-Target Pair
3D Structure (crystal)TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha5-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity for human GABA-A receptor alpha-3-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity against alpha3-beta3-gamma2 GABAA/BzR receptor subtype.More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by PDSP Ki Database
Merck Sharp & Dohme Research Laboratories
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha2-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Binding affinity of the compound tested against alpha2-beta3-gamma2 GABAA/BzR receptor subtype.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4 [36-554]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 3.10nM ΔG°: -48.1kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Binding affinity for human GABA-A receptor alpha-1-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Binding affinity against alpha1-beta3-gamma2 GABAA/BzR receptor subtype.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Binding affinity for human GABA-A receptor alpha-6-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-6-beta-3-gamma-2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Binding affinity against Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha6-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6 [20-453]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison
University of Wisconsin At Madison
Affinity DataKi: 5.10nM ΔG°: -46.9kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]Ro-154513 from GABA-A receptor alpha-6-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]-Ro- 15-4513 from alpha-6-beta-2-gamma-2 GABA-A receptor subunits expressed in Sf9 cell membranesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by PDSP Ki Database
Merck Sharp & Dohme Research Laboratories
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by PDSP Ki Database
Merck Sharp & Dohme Research Laboratories
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]Flunitrazepam from GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:In vitro binding affinity for human GABA-A receptor alpha1-beta3-gamma2 subunits expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by PDSP Ki Database
Merck Sharp & Dohme Research Laboratories
Curated by PDSP Ki Database
Affinity DataEC50: 1.10nMAssay Description:Activity at rat wild type GABAA alpha1beta2gamma2 receptor expressed in xenopus oocytes assessed as GABA-elicited response by two electrode voltage c...More data for this Ligand-Target Pair
