Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 6D27
TargetProstaglandin D2 receptor 2(Human)
Oxagen

Curated by ChEMBL
LigandPNGBDBM50161745({3-[((R)-4-Fluoro-benzenesulfonyl)-methyl-amino]-1...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of CRTH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin D2 receptor 2(Human)
Oxagen

Curated by ChEMBL
LigandPNGBDBM50161745({3-[((R)-4-Fluoro-benzenesulfonyl)-methyl-amino]-1...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of [3H]PGD-2 binding to human chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin D2 receptor 2(Human)
Oxagen

Curated by ChEMBL
LigandPNGBDBM50161745({3-[((R)-4-Fluoro-benzenesulfonyl)-methyl-amino]-1...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin D2 receptor 2(Human)
Oxagen

Curated by ChEMBL
LigandPNGBDBM50161745({3-[((R)-4-Fluoro-benzenesulfonyl)-methyl-amino]-1...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin D2 receptor 2(Human)
Oxagen

Curated by ChEMBL
LigandPNGBDBM50161745({3-[((R)-4-Fluoro-benzenesulfonyl)-methyl-amino]-1...)
Affinity DataIC50: 3nMAssay Description:Inhibition of beta-arrestin translocation at human chemoattractant receptor-homologous molecule expressed on TH2 cells in BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin D2 receptor 2(Human)
Oxagen

Curated by ChEMBL
LigandPNGBDBM50161745({3-[((R)-4-Fluoro-benzenesulfonyl)-methyl-amino]-1...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of CRTH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin D2 receptor 2(Human)
Oxagen

Curated by ChEMBL
LigandPNGBDBM50161745({3-[((R)-4-Fluoro-benzenesulfonyl)-methyl-amino]-1...)
Affinity DataKi:  6nMAssay Description:Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)