Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 6DAJ
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50541364BDBM50541364(CHEMBL4635548)
Affinity DataIC50: 310nMAssay Description:Inhibition of human full length CYP3A4 assessed using 7-benzyloxy-4 (trifluoromethyl)coumarin as substrate preincubated for 20 mins in presence of NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18121BDBM18121(CHEMBL930 | (2S)-2-amino-4-carbamoylbutanoic acid ...)
Affinity DataIC50: 1.00E+4nMAssay Description:A commercially available P450-GLO Assay kit (Promega Corporation, Madison Wis.) is used to screen various compounds for CYP3A4A inhibition activity. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18121BDBM18121(CHEMBL930 | (2S)-2-amino-4-carbamoylbutanoic acid ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Cytochrome P450 is a large and diverse group of enzymes that catalyze the oxidation of organic substances. Some members of the CYP family contribute ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)