Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 7DHR
TargetBeta-2 adrenergic receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50407517BDBM50407517(CHEMBL1160723 | (-)ISOPROTERENOL | US9492405, 27)
Affinity DataIC50: 0.0500nMT: 2°CAssay Description:To measure beta2-AR mediated inhibition of mitogenesis, HEK-beta2-AR, 1321N1 or U87MG cells were seeded in a 96-well plate at approximately 5,000 cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Guinea pig)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407517BDBM50407517(CHEMBL1160723 | (-)ISOPROTERENOL | US9492405, 27)
Affinity DataEC50:  3nMAssay Description:Activity for Beta-2 adrenergic receptor was assessed from effect on relaxation of guinea pig trachea.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50407517BDBM50407517(CHEMBL1160723 | (-)ISOPROTERENOL | US9492405, 27)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at beta2-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring Rluc2-117-GalphaS/GFP10-Ggamma/Gbeta1 assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50407517BDBM50407517(CHEMBL1160723 | (-)ISOPROTERENOL | US9492405, 27)
Affinity DataEC50:  20nMAssay Description:Agonist activity at beta2-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as incre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50407517BDBM50407517(CHEMBL1160723 | (-)ISOPROTERENOL | US9492405, 27)
Affinity DataEC50:  25nMAssay Description:Agonist activity at beta2-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as incre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50407517BDBM50407517(CHEMBL1160723 | (-)ISOPROTERENOL | US9492405, 27)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]-CGP-12177 from human beta2-adrenergic receptor expressed in CHO cells after 60 mins by radioligand competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-2 adrenergic receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 50407517BDBM50407517(CHEMBL1160723 | (-)ISOPROTERENOL | US9492405, 27)
Affinity DataEC50:  46nMAssay Description:Agonist activity at beta2-adrenergic receptor (unknown origin) expressed in HEK293T cells harboring GFP/Rluc2-tagged beta-arrestin2 assessed as incre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)