Affinity DataEC50: 0.00820nMAssay Description:Agonist activity at kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 0.0190nMAssay Description:Displacement of [3H]DPDPE from human KOR expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0250nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0340nMAssay Description:Agonist activity at kappa opioid receptor in human HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0500nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells after 2 hrs by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0500nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.178nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellum after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.178nMAssay Description:Displacement of [3H]U69,593 from KOR in mouse whole brain membranes without cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
Affinity DataKd: 0.190nMAssay Description:Binding affinity to KOR (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.225nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.225nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.238nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes by micro-beta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at GFP-tagged rat kappa opioid receptor expressed in HEK293 cells assessed as increase in ERK1/2 phosphorylation after 5 mins by Wes...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at FLAG-tagged human kappa opioid receptor expressed in HEK293 cells assessed as increase in ERK1/2 phosphorylation after 5 mins by ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Agonist activity at GFP-tagged rat kappa opioid receptor expressed in HEK293 cells assessed as increase in beta-arrestin mediated p38 phosphorylation...More data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Agonist activity at FLAG-tagged human kappa opioid receptor expressed in HEK293 cells assessed as increase in beta-arrestin mediated p38 phosphorylat...More data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
