Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) for PDB: 8Y92
TargetTransporter(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataKi:  0.700nMAssay Description:Inhibition of [3H]- NE reuptake into rat hippocampal synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataKd:  2nMAssay Description:Equilibrium dissociation constant (KD) for Competitive binding between [3H]- nisoxatine and the compound at human Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataIC50: 3nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTransporter(Rat)
The State University of New York

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataIC50: 5nMAssay Description:Inhibition of norepinephrine uptake at human NET in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTransporter(Rat)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataKi:  5nMAssay Description:Ability to inhibit reuptake of norepinephrine ([3H]NE) at norepinephrine transporter of rat parietal/occipital regionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataIC50: 5nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataIC50: 5.10nMAssay Description:Displacement of Levo[ring-2,5,6-3H]norepinephrine from human cloned NET expressed in HEK293 cells by microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent noradrenaline transporter(Human)
Hong Kong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50366567BDBM50366567(ATOMOXETINE)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)