Affinity DataIC50: 0.610nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory activity of the compound was tested against rat DHFR*More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition Dihydrohydrofolate reductase(DHFR) of rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase (DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibitory activity of the compound was tested against Toxoplasma gondii DHFR*More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity of the compound was tested against Pneumocystis. carinii DHFR*More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 89nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase (DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase (DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 870nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair