Compile Data Set for Download or QSAR
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Found 20 Enz. Inhib. hit(s) with all data for entry = 50040317
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50229787((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of MDM2 binding to p53More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392546(CHEMBL2152330)
Affinity DataIC50:  140nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392531(CHEMBL407632)
Affinity DataIC50:  140nMAssay Description:Inhibition of MDM2 binding to p53More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392535(CHEMBL2152320)
Affinity DataIC50:  160nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392535(CHEMBL2152320)
Affinity DataIC50:  160nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM31197(CHEMBL211045 | Nutlin-3 | med.21724, Compound 186)
Affinity DataIC50:  180nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392535(CHEMBL2152320)
Affinity DataIC50:  260nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392542(CHEMBL2152326)
Affinity DataIC50:  340nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392540(CHEMBL2152324)
Affinity DataIC50:  840nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392543(CHEMBL2152327)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392545(CHEMBL2152329)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392534(CHEMBL2152319)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392544(CHEMBL2152328)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392533(CHEMBL2152318)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392538(CHEMBL2152323)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392536(CHEMBL2152321)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392541(CHEMBL2152325)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392539(CHEMBL2151052)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392537(CHEMBL2152322)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50392532(CHEMBL2152332)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of MDM2 binding to p53More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed