Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50009115
TargetNeutrophil elastase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036127(CHEMBL11391 | {2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of human HLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataKi:  6.90nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525579(CHEMBL4514048)
Affinity DataKi:  43nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036093(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  101nMAssay Description:Inhibition of human HLEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525577(CHEMBL4531577)
Affinity DataKi:  157nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM15790(3-N-[(2S,3S,5R)-1-(3,5-difluorophenyl)-3-hydroxy-5...)
Affinity DataIC50:  30nMAssay Description:Inhibition of BACE-1 (unknown origin) using MPBC125-fused APP as substrate incubated for 1 to 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525576(CHEMBL4556276)
Affinity DataIC50:  120nMAssay Description:Inhibition of BACE-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50517919(CHEMBL4445059)
Affinity DataEC50:  587nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525575(CHEMBL4451045)
Affinity DataEC50:  5nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  80nMAssay Description:Agonist activity at kappa opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  0.0800nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525575(CHEMBL4451045)
Affinity DataEC50:  60nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525578(CHEMBL4516807)
Affinity DataEC50: >10nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at mu opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50517888(CHEMBL4442842)
Affinity DataEC50:  43nMAssay Description:Agonist activity at delta opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50525575(CHEMBL4451045)
Affinity DataEC50: >10nMAssay Description:Agonist activity at kappa opioid receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed