Compile Data Set for Download or QSAR
maximum 50k data
Found 35 Enz. Inhib. hit(s) with all data for entry = 50015607
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50119570(CHEMBL3617731)
Affinity DataKi:  20nMAssay Description:Irreversible inhibition of wild type c-Src (unknown origin) assessed as inhibition constant by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50119569(CHEMBL3617733)
Affinity DataKi:  90nMAssay Description:Irreversible inhibition of wild type c-Src (unknown origin) assessed as inhibition constant by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant CK2alphaMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataIC50:  2nMAssay Description:Inhibition of haspin (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM315480(US10172858, Table 1.4)
Affinity DataIC50:  2nMAssay Description:Inhibition of mTOR (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit gamma(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587770(CHEMBL5188493)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of PKA (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit gamma(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  15nMAssay Description:Inhibition of PKA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50254739(CHEMBL4079223)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant ERK2 expressed in Escherichia coli DH5alpha incubated for 1 hrMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 7(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50507989(CHEMBL4445670)
Affinity DataIC50:  35nMAssay Description:Activation of ERK5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587774(CHEMBL5203051)
Affinity DataIC50:  47nMAssay Description:Inhibition of CK2alpha in human MIA PaCa-2 cells incubated for 5 hrs by western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 7(Mus musculus)
Cha University

Curated by ChEMBL
LigandPNGBDBM50507989(CHEMBL4445670)
Affinity DataIC50:  120nMAssay Description:Activation of ERK5 in MEF cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  158nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit gamma(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587769(CHEMBL5181354)
Affinity DataIC50:  159nMAssay Description:Inhibition of PKA (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587784(CHEMBL5202249)
Affinity DataIC50:  160nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Cha University

Curated by ChEMBL
LigandPNGBDBM50587775(CHEMBL5192851)
Affinity DataIC50:  670nMAssay Description:Inhibition of human CK2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587777(CHEMBL5174190)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant ERK2 expressed in Escherichia coli DH5alpha incubated for 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587783(CHEMBL5206201)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit gamma(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)
Affinity DataIC50:  4.58E+3nMAssay Description:Inhibition of PKA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase II subunit alpha 3(Homo sapiens)
Cha University

Curated by ChEMBL
LigandPNGBDBM50587776(CHEMBL5184966)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human CK2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit gamma(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587768(CHEMBL5172395)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of PKA (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Cha University

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataKd:  296nMAssay Description:Binding affinity to chicken 6-His tagged c-Src expressed in Escherichia coli Bl21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587782(CHEMBL5209202)
Affinity DataKd:  0.280nMAssay Description:Binding affinity to chicken 6-His tagged c-Src expressed in Escherichia coli Bl21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50331791((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydr...)
Affinity DataKd: >1.50E+4nMAssay Description:Binding affinity to a TEV-cleavable N-terminal His6-tagged human recombinant haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587766(CHEMBL5199572)
Affinity DataKd:  0.0190nMAssay Description:Binding affinity to a TEV-cleavable N-terminal His6-tagged human recombinant haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587781(CHEMBL5169980)
Affinity DataKd:  4nMAssay Description:Binding affinity to a TEV-cleavable N-terminal His6-tagged human recombinant haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587780(CHEMBL5209851)
Affinity DataKd:  170nMAssay Description:Binding affinity to N-terminal his6-tagged human recombinant Haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587779(CHEMBL5194339)
Affinity DataKd:  0.420nMAssay Description:Binding affinity to N-terminal his6-tagged human recombinant Haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587778(CHEMBL5198165)
Affinity DataKd:  150nMAssay Description:Binding affinity to N-terminal his6-tagged human recombinant Haspin (470 to 798 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587773(CHEMBL5190946)
Affinity DataKd:  0.0130nMAssay Description:Binding affinity to human wild-type PKAc beta assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587772(CHEMBL5185265)
Affinity DataKd:  0.0420nMAssay Description:Displacement of mAb(D38C6)-BTN from human recombinant PKAc alpha incubated for 15 mins by microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587771(CHEMBL5183651)
Affinity DataKd:  30nMAssay Description:Inhibition of ROCK2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetcAMP-dependent protein kinase catalytic subunit gamma(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587771(CHEMBL5183651)
Affinity DataKd:  0.100nMAssay Description:Binding affinity to PKA (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEphrin type-A receptor 3(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataKd:  2.00E+5nMAssay Description:Inhibition of EPHA3 (unknown origin) assessed as dissociation constant by ELISA-like binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587766(CHEMBL5199572)
Affinity DataKd:  0.0190nMAssay Description:Binding affinity to haspin (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEphrin type-A receptor 3(Homo sapiens (Human))
Cha University

Curated by ChEMBL
LigandPNGBDBM50587767(CHEMBL5172097)
Affinity DataKd:  250nMAssay Description:Inhibition of EPHA3 (unknown origin) assessed as dissociation constant by ELISA-like binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed