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Found 30 Enz. Inhib. hit(s) with all data for entry = 50016858
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3758(N-(3-Bromophenyl)-6-methoxy-1H-pyrimido[4,5-b]indo...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597827(CHEMBL5184038)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597830(CHEMBL5183413)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597828(CHEMBL5187154)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597822(CHEMBL5175208)
Affinity DataIC50:  9nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597826(CHEMBL5169624)
Affinity DataIC50:  10nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5323(1-[3-(4-methylpiperazin-1-yl)propyl]-3-[5-(thiophe...)
Affinity DataIC50:  16nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597829(CHEMBL5171763)
Affinity DataIC50:  21nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597820(CHEMBL423224)
Affinity DataIC50:  31nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597823(CHEMBL5172665)
Affinity DataIC50:  31nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5322(1-[3-(piperidin-1-yl)propyl]-3-[5-(thiophen-3-yl)p...)
Affinity DataIC50:  38nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597824(CHEMBL5202879)
Affinity DataIC50:  40nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5324(3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3g | dimethy...)
Affinity DataIC50:  64nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3744(N-(3-bromophenyl)-5H-pyrimido[5,4-b]indol-4-amine ...)
Affinity DataIC50:  72nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597825(CHEMBL5199108)
Affinity DataIC50:  84nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5320(1-[2-(piperidin-1-yl)ethyl]-3-[5-(thiophen-3-yl)py...)
Affinity DataIC50:  111nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5319(3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3b | dimethy...)
Affinity DataIC50:  115nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM5318(3-(5-Thien-3-ylpyridin-3-yl)-1Hindole 3a | 3-[5-(t...)
Affinity DataIC50:  126nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3746(N-benzyl-5H-pyrimido[5,4-b]indol-4-amine | Pyrimid...)
Affinity DataIC50:  460nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM4000(1 H-indole-3-alkanamide deriv. 10i | 2,2-Dithiobis...)
Affinity DataIC50:  850nMAssay Description:Inhibition of EGFR derived from human A-431 cell membrane vesicles using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597831(CHEMBL5182427)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of p60 c-src (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3985(2,2 -Dithiobis(7-methyl-1H-indole-3-propanoic acid...)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of 32P-labeled ATP from EGFR derived from human A-431 cell membrane vesicles using copolymer of Glu/Ala/Tyr as substrate incubated for 1...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597821(CHEMBL309276)
Affinity DataIC50:  1.62E+3nMAssay Description:Displacement of 32P-labeled ATP from EGFR derived from human A-431 cell membrane vesicles using copolymer of Glu/Ala/Tyr as substrate incubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM4033(6-methoxy-2-{[6-methoxy-1-methyl-3-(phenylcarbamoy...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3750(Pyrimido[5,4-b]indole deriv. 41 | dimethyl(2-{5H-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM3749(N-cyclohexyl-5H-pyrimido[5,4-b]indol-4-amine | Pyr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597819(CHEMBL5205062)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM4032(2-{[1,6-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM4024(2-{[1,5-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Dr. Harisingh Gour University

Curated by ChEMBL
LigandPNGBDBM50597832(CHEMBL5184360)
Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of src (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed