TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 129nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 209nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 263nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 282nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 363nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 417nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 692nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 741nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 891nMAssay Description:Agonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.29E+3nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.51E+3nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.51E+3nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 2.69E+3nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 2.75E+3nMAssay Description:Agonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 3.98E+3nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 4.27E+3nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 5.37E+3nMAssay Description:Agonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 5.62E+3nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 6.31E+3nMAssay Description:Antagonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followe...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 6.46E+3nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 4(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Agonist activity at human P2X4R expressing HEK293 cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2/3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.15E+4nMAssay Description:Antagonist activity at human P2X2R/P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr foll...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.58E+4nMAssay Description:Antagonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 1.86E+4nMAssay Description:Antagonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 2.63E+4nMAssay Description:Antagonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed b...More data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: 3.02E+4nMAssay Description:Agonist activity at human P2X3R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair
TargetP2X purinoceptor 2(Homo sapiens (Human))
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
European Institute For Molecular Imaging (Eimi)
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by c...More data for this Ligand-Target Pair