Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 10685
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559792(WO2022109182, Example 23)
Affinity DataIC50:  0.0300nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559790(WO2022109182, Example 21)
Affinity DataIC50:  0.0400nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559789(2-[[4-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-5-fluo...)
Affinity DataIC50:  0.0700nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559791(2-[[4-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-5-fluo...)
Affinity DataIC50:  0.220nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559784(WO2022109182, Example 15)
Affinity DataIC50:  0.240nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559788(2-[[4-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyri...)
Affinity DataIC50:  0.300nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559793(6-(tert-butoxycarbonylamino)-2-[[4-[6-[(4-cyano-2-...)
Affinity DataIC50:  0.510nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559781(WO2022109182, Example 12)
Affinity DataIC50:  0.810nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559787(2-[[4-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyri...)
Affinity DataIC50:  0.980nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559783(2-(6-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl)...)
Affinity DataIC50:  1.04nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559773(Methyl (S)-2-((4-(2-((4-cyano-2-fluorobenzyl)oxy)p...)
Affinity DataIC50:  1.20nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559780(2-[[4-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyri...)
Affinity DataIC50:  1.70nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559772(2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl...)
Affinity DataIC50:  1.90nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559778(WO2022109182, Example 9)
Affinity DataIC50:  2.60nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559775(WO2022109182, Example 6)
Affinity DataIC50:  2.60nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559794(WO2022109182, Example 25)
Affinity DataIC50:  3.5nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559776(2-[6-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyrid...)
Affinity DataIC50:  3.80nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559777(WO2022109182, Example 8)
Affinity DataIC50:  5.30nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559778(WO2022109182, Example 9)
Affinity DataIC50:  6.60nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559794(WO2022109182, Example 25)
Affinity DataIC50:  7.10nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559774(Methyl 2-[[4-[6-[(4-cyano-2-fluoro-phenyl)methoxy]...)
Affinity DataIC50:  9.80nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559776(2-[6-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyrid...)
Affinity DataIC50:  10nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559779(2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl...)
Affinity DataIC50:  11nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559801(WO2022109182, Example 32)
Affinity DataIC50:  11nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559786(Methyl (S)-2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)p...)
Affinity DataIC50:  13nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559777(WO2022109182, Example 8)
Affinity DataIC50:  13nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559769(2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl...)
Affinity DataIC50:  15nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559796(WO2022109182, Example 27)
Affinity DataIC50:  15nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559779(2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl...)
Affinity DataIC50:  18nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559797(WO2022109182, Example 28)
Affinity DataIC50:  21nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559785(Methyl (S)-2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)p...)
Affinity DataIC50:  29nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559782(2-[[4-[6-[(4-carbamoyl-2-fluoro-phenyl)methoxy]-2-...)
Affinity DataIC50:  32nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559795(WO2022109182, Example 26)
Affinity DataIC50:  48nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559799(2-[[4-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyri...)
Affinity DataIC50:  52nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559795(WO2022109182, Example 26)
Affinity DataIC50:  54nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559798(WO2022109182, Example 29)
Affinity DataIC50:  104nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559800(2-(((1s,4s)-4-(6-((4-cyano-2-fluorobenzyl)oxy)pyri...)
Affinity DataIC50:  134nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Gilead Sciences

WIPO
LigandPNGBDBM559771(WO2022109182, Example 2)
Affinity DataIC50:  175nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed