Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50190120
Substrate
n/a
Meas. Tech.
ChEBML_1685096
Ki
32±n/a nM
Citation
 Knappmann, I; Lehmkuhl, K; Köhler, J; Schepmann, D; Giera, M; Bracher, F; Wünsch, B Lipase-catalyzed kinetic resolution as key step in the synthesis of enantiomerically pure? ligands with 2-benzopyran structure. Bioorg Med Chem 25:3384-3395 (2017) [PubMed]  Article 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50190120
Synonyms:
CHEMBL3828752
Type:
Small organic molecule
Emp. Form.:
C25H31NO3
Mol. Mass.:
393.5185
SMILES:
COC(=O)C[C@@H]1Cc2ccccc2[C@H](CCN2CCC(CC2)c2ccccc2)O1 |r|
Structure:
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