Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50260583
Substrate
n/a
Meas. Tech.
ChEBML_1694032
Ki
8.6±n/a nM
Citation
 Fanter, L; Müller, C; Schepmann, D; Bracher, F; Wünsch, B Chiral-pool synthesis of 1,2,4-trisubstituted 1,4-diazepanes as novel? Bioorg Med Chem 25:4778-4799 (2017) [PubMed]  Article 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM50260583
Synonyms:
CHEMBL4094304
Type:
Small organic molecule
Emp. Form.:
C23H32N2
Mol. Mass.:
336.5136
SMILES:
C[C@H]1CN(CCCCc2ccccc2)CCCN1Cc1ccccc1 |r|
Structure:
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