Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50260590
Substrate
n/a
Meas. Tech.
ChEBML_1694030
Ki
6.0±n/a nM
Citation
 Fanter, L; Müller, C; Schepmann, D; Bracher, F; Wünsch, B Chiral-pool synthesis of 1,2,4-trisubstituted 1,4-diazepanes as novel? Bioorg Med Chem 25:4778-4799 (2017) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50260590
Synonyms:
CHEMBL4099831
Type:
Small organic molecule
Emp. Form.:
C22H36N2
Mol. Mass.:
328.5346
SMILES:
CC(C)[C@H]1CN(CC2CCCCC2)CCCN1Cc1ccccc1 |r|
Structure:
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