Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50433728
Substrate
n/a
Meas. Tech.
ChEMBL_959727 (CHEMBL2383047)
EC50
57±n/a nM
Citation
 Lu, H; Fei, H; Yang, F; Zheng, S; Hu, Q; Zhang, L; Yuan, J; Feng, J; Sun, P; Dong, Q Discovery of novel orally bioavailable GPR40 agonists. Bioorg Med Chem Lett 23:2920-4 (2013) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50433728
Synonyms:
CHEMBL2381310
Type:
Small organic molecule
Emp. Form.:
C24H19ClO5
Mol. Mass.:
422.858
SMILES:
OC(=O)C[C@@H]1COc2cc3O[C@H](COc3cc12)c1cccc(c1)-c1ccccc1Cl |r|
Structure:
Search PDB for entries with ligand similarity: