Reaction Details Report a problem with these data
Target
Metabotropic glutamate receptor 4
Ligand
BDBM17660
Substrate
n/a
Meas. Tech.
ChEMBL_106690 (CHEMBL714671)
EC50
>100000±n/a nM
Citation
 Knöpfel, T; Kuhn, R; Allgeier, H Metabotropic glutamate receptors: novel targets for drug development. J Med Chem 38:1417-26 (1995) [PubMed]  Article 
Target
Name:
Metabotropic glutamate receptor 4
Synonyms:
GRM4_RAT | Gprc1d | Grm4 | Metabotropic glutamate receptor | Metabotropic glutamate receptor 4 (mGlu4) | Mglur4 | mGlu4 | metabotropic glutamate 4 | metabotropic glutamate 4a
Type:
Enzyme
Mol. Mass.:
101849.79
Organism:
Rattus norvegicus (Rat)
Description:
P31423
Residue:
912
Sequence:
MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQKSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIAATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALATKQTYVTYTNHAI
  
Inhibitor
Name:
BDBM17660
Synonyms:
(2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid | 2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)propionic acid | CHEMBL279956 | Quisqualate | Quisqualate, L | quisqualic acid
Type:
Small organic molecule
Emp. Form.:
C5H7N3O5
Mol. Mass.:
189.1262
SMILES:
N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: