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Target
Cholecystokinin
Ligand
BDBM50019274
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_17
Citation
 Evans, BE; Bock, MG; Rittle, KE; DiPardo, RM; Whitter, WL; Veber, DF; Anderson, PS; Freidinger, RM Design of potent, orally effective, nonpeptidal antagonists of the peptide hormone cholecystokinin. Proc Natl Acad Sci U S A 83:4918-22 (1986) [PubMed]  Article 
Target
Name:
Cholecystokinin
Synonyms:
CCKN_RAT | Cck
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12844.29
Organism:
RAT
Description:
Cholecystokinin 0 RAT::P01355
Residue:
115
Sequence:
MKCGVCLCVVMAVLAAGALAQPVVPVEAVDPMEQRAEEAPRRQLRAVLRPDSEPRARLGALLARYIQQVRKAPSGRMSVLKNLQGLDPSHRISDRDYMGWMDFGRRSAEDYEYPS
  
Inhibitor
Name:
BDBM50019274
Synonyms:
CCK antagonist synthetic 16 | CHEMBL72057 | N-[5-(2-Fluoro-phenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-acetamide
Type:
Small organic molecule
Emp. Form.:
C17H14FN3O2
Mol. Mass.:
311.3104
SMILES:
CC(=O)NC1N=C(c2ccccc2F)c2ccccc2NC1=O |t:5|
Structure:
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