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Target
D-amino-acid oxidase
Ligand
BDBM50232880
Substrate
n/a
Meas. Tech.
ChEMBL_1768982 (CHEMBL4221094)
IC50
418±n/a nM
Citation
 Szilágyi, B; Kovács, P; Ferenczy, GG; Rácz, A; Németh, K; Visy, J; Szabó, P; Ilas, J; Balogh, GT; Monostory, K; Vincze, I; Tábi, T; Szök?, É; Keser?, GM Discovery of isatin and 1H-indazol-3-ol derivatives as d-amino acid oxidase (DAAO) inhibitors. Bioorg Med Chem 26:1579-1587 (2018) [PubMed]  Article 
Target
Name:
D-amino-acid oxidase
Synonyms:
D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN
Type:
Homodimer
Mol. Mass.:
39476.06
Organism:
Homo sapiens (Human)
Description:
P14920
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
  
Inhibitor
Name:
BDBM50232880
Synonyms:
Benzo[D]Isoxazol-3-Ol | CHEMBL444173
Type:
Small organic molecule
Emp. Form.:
C7H5NO2
Mol. Mass.:
135.1201
SMILES:
Oc1noc2ccccc12
Structure:
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