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Target
D(2) dopamine receptor
Ligand
BDBM50002245
Substrate
n/a
Meas. Tech.
ChEMBL_59474 (CHEMBL671727)
Ki
>1000±n/a nM
Citation
 Schuster, DI; Pan, YP; Singh, G; Stoupakis, G; Cai, B; Lem, G; Ehrlich, GK; Frietze, W; Murphy, RB N-(1-arylpropionyl)-4-aryltetrahydropyridines, a new class of high-affinity selective sigma receptor ligands. J Med Chem 36:3923-8 (1994) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50698.79
Organism:
BOVINE
Description:
P20288
Residue:
444
Sequence:
MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50002245
Synonyms:
4-[2-(1-Cyclopropylmethyl-piperidin-4-yl)-acetyl]-benzonitrile; compound with but-2-enedioic acid | CHEMBL130356 | CHEMBL137776
Type:
Small organic molecule
Emp. Form.:
C18H22N2O
Mol. Mass.:
282.3801
SMILES:
O=C(CC1CCN(CC2CC2)CC1)c1ccc(cc1)C#N
Structure:
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