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Target
Cyclin-dependent kinase 1
Ligand
BDBM50056161
Substrate
n/a
Meas. Tech.
ChEMBL_48699 (CHEMBL657992)
IC50
200000±n/a nM
Citation
 Havlícek, L; Hanus, J; Veselý, J; Leclerc, S; Meijer, L; Shaw, G; Strnad, M Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds. J Med Chem 40:408-12 (1997) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 1
Synonyms:
CDC2 | CDC28A | CDK1 | CDK1_HUMAN | CDKN1 | Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | P34CDC2 | p34 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
34101.08
Organism:
Homo sapiens (Human)
Description:
P06493
Residue:
297
Sequence:
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
  
Inhibitor
Name:
BDBM50056161
Synonyms:
2-(6-Amino-9H-purin-2-ylamino)-ethanol | CHEMBL130306
Type:
Small organic molecule
Emp. Form.:
C7H10N6O
Mol. Mass.:
194.1939
SMILES:
Nc1nc(NCCO)nc2nc[nH]c12
Structure:
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