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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50064201
Substrate
n/a
Meas. Tech.
ChEMBL_158768 (CHEMBL772929)
Ki
0.16±n/a nM
Citation
 Martin, SF; Dorsey, GO; Gane, T; Hillier, MC; Kessler, H; Baur, M; Mathä, B; Erickson, JW; Bhat, TN; Munshi, S; Gulnik, SV; Topol, IA Cyclopropane-derived peptidomimetics. Design, synthesis, evaluation, and structure of novel HIV-1 protease inhibitors. J Med Chem 41:1581-97 (1998) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50064201
Synonyms:
1N-benzyl-2N-[1-benzyl-4-(2-benzylcarbamoyl-3-methylcyclopropylcarboxamido)-2,3-dihydroxy-5-phenylpentyl]-3-methyl-1,2-cyclopropanedicarboxamide | CHEMBL433446
Type:
Small organic molecule
Emp. Form.:
C44H50N4O6
Mol. Mass.:
730.891
SMILES:
C[C@H]1[C@H]([C@@H]1C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1[C@@H](C)[C@H]1C(=O)NCc1ccccc1)C(=O)NCc1ccccc1
Structure:
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