Affinity DataKi: 0.00400nM ΔG°: -66.1kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0110nM ΔG°: -63.6kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
Affinity DataKi: 0.0120nM ΔG°: -63.4kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0210nM IC50: 0.170nMAssay Description:The Ki value were determine by a fluorometric assay with the fluorogenic and chromogenic substrate.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nM ΔG°: -62.5kJ/molepH: 6.2 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0400nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0600nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0700nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
Affinity DataKi: 0.0900nMAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0900nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.0900nMAssay Description:Compound was evaluated for the inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.110nMAssay Description:Inhibitory activity of the compound was measured against wild-type HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.112nM ΔG°: -57.7kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Compound was evaluated for the inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Compound was evaluated for the inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Inhibitory activity of the compound was measured against wild-type HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Inhibitory activity of the compound was measured against wild-type HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nM ΔG°: -58.0kJ/molepH: 6.2 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Compound was evaluated for the inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Compound was evaluated for the inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.260nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.270nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.310nMAssay Description:Inhibitory activity of the compound was measured against wild-type HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nM IC50: 0.630nMAssay Description:The Ki value were determine by a fluorometric assay with the fluorogenic and chromogenic substrate.More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Compound was evaluated for the inhibitory constant towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.450nMAssay Description:Tested for inhibition of HIV protease using fluorogenic substrateMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.450nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Inhibitory activity of the compound was measured against wild-type HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.610nMAssay Description:Compound was evaluated for the affinity towards Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.620nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Aids Drug Screening And Development Laboratory
Curated by ChEMBL
Affinity DataKi: 0.680nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair