Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50513137
Substrate
n/a
Meas. Tech.
ChEMBL_1852096 (CHEMBL4352720)
IC50
480±n/a nM
Citation
 Niu, H; Strecker, TE; Gerberich, JL; Campbell, JW; Saha, D; Mondal, D; Hamel, E; Chaplin, DJ; Mason, RP; Trawick, ML; Pinney, KG Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization. J Med Chem 62:5594-5615 (2019) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50513137
Synonyms:
CHEMBL3093134
Type:
Small organic molecule
Emp. Form.:
C21H22O5
Mol. Mass.:
354.3964
SMILES:
COc1ccc2c(CC=CC=C2c2cc(OC)c(OC)c(OC)c2)c1O |c:8,10|
Structure:
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