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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50071619
Substrate
n/a
Meas. Tech.
ChEBML_159306
IC50
10±n/a nM
Citation
 Ro, S; Baek, SG; Lee, B; Park, C; Choy, N; Lee, CS; Son, YC; Choi, H; Koh, JS; Yoon, H; Kim, SC; Ok, JH NMR and topochemical studies of peptidomimetic HIV-I protease inhibitors containing a cis-epoxide amide isostere. Bioorg Med Chem Lett 8:2423-6 (1999) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50071619
Synonyms:
(S)-N*1*-((S)-1-{(2R,3S)-3-[((R)-1-Methoxycarbamoyl-2-methyl-propylcarbamoyl)-methyl]-oxiranyl}-2-phenyl-ethyl)-2-[(quinoline-2-carbonyl)-amino]-succinamide | CHEMBL78312
Type:
Small organic molecule
Emp. Form.:
C32H38N6O7
Mol. Mass.:
618.6801
SMILES:
CONC(=O)[C@H](NC(=O)C[C@@H]1O[C@@H]1[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1)C(C)C
Structure:
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