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Found 405 with Last Name = 'koh' and Initial = 'js'
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50284986(CHEMBL55197 | [(R)-1-((S)-1-{(2R,3S)-3-[((S)-2-Ben...)
Affinity DataKi:  0.100nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288943(CHEMBL154519 | Quinoline-2-carboxylic acid {(R)-1-...)
Affinity DataKi:  0.113nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288941((3S,4aS,8aS)-2-((2R,3S)-2-Hydroxy-3-{(R)-2-[2-(5-h...)
Affinity DataKi:  0.151nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288942(CHEMBL154692 | {(R)-1-[(1S,2R)-1-Benzyl-3-((3S,4aS...)
Affinity DataKi:  0.162nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288939(CHEMBL345187 | Quinoline-2-carboxylic acid {(R)-1-...)
Affinity DataKi:  0.172nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM519((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...)
Affinity DataKi:  0.452nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM9294((3S,4aS,8aS)-N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[...)
Affinity DataKi:  0.550nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290520(((R)-1-{(S)-1-[(2R,3S)-3-(2-tert-Butylsulfamoyl-et...)
Affinity DataKi:  0.700nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290527(CHEMBL86971 | [(R)-1-((S)-1-{(2R,3S)-3-[2-(Ethyl-i...)
Affinity DataKi:  0.800nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50009242(CHEMBL48565 | {(S)-1-[(1S,2S,3R,4S)-1-Benzyl-4-((S...)
Affinity DataKi: <1nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM197((2S)-N-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[(2S)-3-meth...)
Affinity DataKi: <1nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288940(CHEMBL154416 | Quinoline-2-carboxylic acid {(R)-1-...)
Affinity DataKi:  2.60nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290525(CHEMBL92097 | [(R)-1-((S)-1-{(2R,3S)-3-[2-(Ethyl-i...)
Affinity DataKi:  2.90nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290523(CHEMBL327222 | Thiophene-2-carboxylic acid [(R)-1-...)
Affinity DataKi:  3.10nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290524(CHEMBL404933 | [(R)-1-((S)-1-{(2R,3S)-3-[2-(Benzoy...)
Affinity DataKi:  3.60nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50284988(CHEMBL52809 | [(S)-1-(1-{(2S,3R)-3-[(S)-1-((R)-2-B...)
Affinity DataKi:  4nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290526(CHEMBL328036 | [(R)-1-((S)-1-{(2R,3S)-3-[2-(Ethyl-...)
Affinity DataKi:  4.60nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290522(CHEMBL313237 | Quinoline-2-carboxylic acid [(R)-1-...)
Affinity DataKi:  5nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290521(CHEMBL89076 | Quinoline-2-carboxylic acid [(R)-1-(...)
Affinity DataKi:  7nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069055((S)-3-(4-Aminomethyl-phenyl)-N-cyclopentyl-N-methy...)
Affinity DataKi:  10nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50284989(CHEMBL300705 | {(R)-2-Methyl-1-[(S)-1-((2R,3S)-3-{...)
Affinity DataKi:  11nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290528(CHEMBL261900 | N*1*-{(S)-1-[(2R,3S)-3-(2-tert-Buty...)
Affinity DataKi:  13nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50284984((R)-3-Methyl-N-[(S)-1-((2R,3S)-3-{[(S)-3-methyl-2-...)
Affinity DataKi:  16nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069053((S)-3-(4-Aminomethyl-phenyl)-N-cyclopentyl-N-methy...)
Affinity DataKi:  50nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50284987(CHEMBL293061 | {(R)-2-Methyl-1-[(S)-1-((2R,3S)-3-{...)
Affinity DataKi:  70nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50284991(CHEMBL295499 | [(S)-1-((S)-1-{3-[(S)-1-((S)-2-Benz...)
Affinity DataKi:  75nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCytochrome P450 3A4(Homo sapiens (Human))
Lg Life Sciences R & D Center

Curated by ChEMBL
LigandPNGBDBM50106864((1-((1-(benzo[d][1,3]dioxol-5-ylmethyl)-1H-imidazo...)
Affinity DataKi:  80nMAssay Description:Reversible inhibition of human CYP3A4 in liver microsomes by Dixon and Cornish-Bowden plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069052(CHEMBL164661 | Naphthalene-2-sulfonic acid [(S)-1-...)
Affinity DataKi:  200nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50284990(CHEMBL54394 | {(R)-2-Methyl-1-[(S)-1-((2R,3S)-3-{[...)
Affinity DataKi:  300nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069051((S)-3-(4-Aminomethyl-phenyl)-N-isopropyl-N-methyl-...)
Affinity DataKi:  600nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069057((S)-3-(4-Aminomethyl-phenyl)-N,N-dimethyl-2-(napht...)
Affinity DataKi:  3.06E+3nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069056(CHEMBL350751 | Naphthalene-2-sulfonic acid [(S)-1-...)
Affinity DataKi:  1.56E+4nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069054((S)-3-(4-Aminomethyl-phenyl)-N-isopropyl-2-(naphth...)
Affinity DataKi:  3.17E+4nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50069050((S)-3-(4-Aminomethyl-phenyl)-N-benzyl-2-(naphthale...)
Affinity DataKi:  9.72E+4nMAssay Description:Inhibition constant was evaluated for inhibitory activity against the blood coagulant thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50284985(1,2-Epoxy-3-(4'-nitrophenoxy)propane | 1,2-Epoxy-3...)
Affinity DataKi:  1.10E+7nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181249(5-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(nap...)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181245(3-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(nap...)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Genosco

US Patent
LigandPNGBDBM138212(US8871778, 198)
Affinity DataIC50:  0.100nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Genosco

US Patent
LigandPNGBDBM138211(US8871778, 190)
Affinity DataIC50:  0.100nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181261(3-(3-(1H-imidazol-1-yl)propyl)-1-(4-bromobenzyl)-5...)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181255(4-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(nap...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50384024(CHEMBL2032280 | CHEMBL2079349)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of recombinant c-Met by time resolved-fluorescence resonance energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181252(3-(3-(1H-imidazol-1-yl)propyl)-1-(4-(methylthiomet...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181239(3-(3-(1H-imidazol-1-yl)propyl)-1-(3-chlorobenzyl)-...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181248(CHEMBL381490 | N-(4-((3-(3-(1H-imidazol-1-yl)propy...)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181258(3-(3-(1H-imidazol-1-yl)propyl)-1-(3-bromobenzyl)-5...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50181246(CHEMBL206795 | N-(2-((3-(3-(1H-imidazol-1-yl)propy...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50067584((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of [3H]-FPP incorporation into Ha-ras protein by FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50384038(CHEMBL2032155)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of recombinant FLT3 by time resolved-fluorescence resonance energy transfer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Genosco

US Patent
LigandPNGBDBM138217(US8871778, 251)
Affinity DataIC50:  0.600nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In DepthDetails US Patent
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