Reaction Details Report a problem with these data
Target
DNA repair protein RAD52 homolog
Ligand
BDBM50565805
Substrate
n/a
Meas. Tech.
ChEMBL_2093901 (CHEMBL4775164)
IC50
<5000±n/a nM
Citation
 Myers, SH; Ortega, JA; Cavalli, A Synthetic Lethality through the Lens of Medicinal Chemistry. J Med Chem 63:14151-14183 (2020) [PubMed]  Article 
Target
Name:
DNA repair protein RAD52 homolog
Synonyms:
DNA repair protein RAD52 homolog | RAD52 | RAD52_HUMAN
Type:
PROTEIN
Mol. Mass.:
46177.71
Organism:
Homo sapiens
Description:
ChEMBL_105690
Residue:
418
Sequence:
MSGTEEAILGGRDSHPAAGGGSVLCFGQCQYTAEEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDLNNGKFYVGVCAFVRVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLRSLNKLPRQLPLEVDLTKAKRQDLEPSVEEARYNSCRPNMALGHPQLQQVTSPSRPSHAVIPADQDCSSRSLSSSAVESEATHQRKLRQKQLQQQFRERMEKQQVRVSTPSAEKSEAAPPAPPVTHSTPVTVSEPLLEKDFLAGVTQELIKTLEDNSEKWAVTPDAGDGVVKPSSRADPAQTSDTLALNNQMVTQNRTPHSVCHQKPQAKSGSWDLQTYSADQRTTGNWESHRKSQDMKKRKYDPS
  
Inhibitor
Name:
BDBM50565805
Synonyms:
CHEMBL4785153
Type:
Small organic molecule
Emp. Form.:
C11H10O4
Mol. Mass.:
206.1947
SMILES:
CC(C)Oc1c(-c2ccco2)c(=O)c1=O
Structure:
Search PDB for entries with ligand similarity: