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Target
D(4) dopamine receptor
Ligand
BDBM50132692
Substrate
n/a
Meas. Tech.
ChEMBL_63102 (CHEMBL674495)
Ki
27.0±n/a nM
Citation
 Einsiedel, J; Weber, K; Thomas, C; Lehmann, T; Hübner, H; Gmeiner, P Stereocontrolled dopamine receptor binding and subtype selectivity of clebopride analogues synthesized from aspartic acid. Bioorg Med Chem Lett 13:3293-6 (2003) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50132692
Synonyms:
4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((3R,4R)-1-benzyl-4-methyl-pyrrolidin-3-yl)-amide | CHEMBL321492
Type:
Small organic molecule
Emp. Form.:
C24H25BrN2O2
Mol. Mass.:
453.372
SMILES:
COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CN(Cc2ccccc2)C[C@H]1C
Structure:
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