Target
Lysophosphatidic acid receptor 1
Ligand
BDBM50193517
Substrate
n/a
Meas. Tech.
ChEMBL_385201 (CHEMBL868013)
Ki
403±n/a nM
Citation
 Xu, YJiang, GTsukahara, RFujiwara, YTigyi, GPrestwich, GD Phosphonothioate and fluoromethylene phosphonate analogues of cyclic phosphatidic acid: Novel antagonists of lysophosphatidic acid receptors. J Med Chem 49:5309-15 (2006) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 1
Synonyms:
EDG2 | LPA receptor 1 | LPA-1 | LPA1 | LPAR1 | LPAR1_HUMAN | Lysophosphatidic acid receptor 1 (LPA1) | Lysophosphatidic acid receptor Edg-2
Type:
Enzyme
Mol. Mass.:
41120.55
Organism:
Homo sapiens (Human)
Description:
Q92633
Residue:
364
Sequence:
MAAISTSIPVISQPQFTAMNEPQCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGVHSNDHSVV
  
Inhibitor
Name:
BDBM50193517
Synonyms:
3-hydroxyl-4-oleoyloxylbutane 1,3-cyclic phosphonothioate | CHEMBL212029
Type:
Small organic molecule
Emp. Form.:
C22H43O4PS
Mol. Mass.:
434.613
SMILES:
CCCCCCCCCCCCCCCCCC(=O)OCC1CCP(O)(=S)O1
Structure:
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