TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Apparent inhibitory constant of the compound against squalene epoxidaseMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
Affinity DataKi: 60.7nMAssay Description:Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
Affinity DataKi: 314nMAssay Description:Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataKi: 403nMAssay Description:Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 512nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
Affinity DataKi: 636nMAssay Description:Activity at human LPA3 receptor expressed in RH7777 cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 834nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 1.01E+3nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
Affinity DataKi: 1.15E+3nMAssay Description:Activity at human LPA3 receptor expressed in RH7777 cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 1.79E+3nMAssay Description:Inhibition of human ATX phosphodiesterase expressed in Sf9 cells assessed as hydrolysis of FS-3 measured after 5 to 25 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nMpH: 8.8Assay Description:The compound was tested for its inhibitory activity against pig Squalene epoxidase at pH 7.4More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 2.43E+3nMAssay Description:Inhibition of human ATX phosphodiesterase expressed in Sf9 cells assessed as hydrolysis of FS-3 measured after 5 to 25 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
Affinity DataKi: 3.17E+3nMAssay Description:Activity at human LPA3 receptor expressed in RH7777 cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 3.50E+3nMAssay Description:Inhibition of human ATX phosphodiesterase expressed in Sf9 cells assessed as hydrolysis of FS-3 measured after 5 to 25 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:Inhibitory activity of the compound was measured against partially purified pig liver Squalene epoxidase (SE).More data for this Ligand-Target Pair
Affinity DataKi: 4.40E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+3nMAssay Description:Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
The University Of Utah
Curated by ChEMBL
The University Of Utah
Curated by ChEMBL
Affinity DataKi: 8.80E+3nMAssay Description:Dissociation constant against yeast farnesyltransferaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.02E+4nMAssay Description:Concentration that cause 50 percent inhibition of binding of [14C]-labeled (3S)-oxidosqualene to isolated rat liver oxidosqualene cyclase (OSC) was d...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Compound was evaluated for the binding affinity against rat liver oxidosqualene cyclase (OSC)More data for this Ligand-Target Pair
Affinity DataKi: 6.00E+4nMAssay Description:Inhibition constant against rat liver Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
Affinity DataKi: 9.50E+5nMAssay Description:Apparent inhibitory constant of the compound against squalene epoxidaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+6nMAssay Description:Inhibitory activity against Candida albicans Squalene EpoxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from Candida albicansMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from Candida albicansMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in T. bruceiMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in P. cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in T. bruceiMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in ratMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in T. cruziMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in P. cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 106nMAssay Description:Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition against rat liver Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in ratMore data for this Ligand-Target Pair