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Target
Cyclin-dependent kinase inhibitor 1
Ligand
BDBM50609125
Substrate
n/a
Meas. Tech.
ChEMBL_2276640
IC50
760±n/a nM
Citation
 Mancini, RS; Barden, CJ; Weaver, DF; Reed, MA Furazans in Medicinal Chemistry. J Med Chem 64:1786-1815 (2021) [PubMed] 
Target
Name:
Cyclin-dependent kinase inhibitor 1
Synonyms:
CAP20 | CDK-interacting protein 1 | CDKN1 | CDKN1A | CDN1A_HUMAN | CIP1 | MDA6 | PIC1 | SDI1 | WAF1
Type:
PROTEIN
Mol. Mass.:
18123.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_312386
Residue:
164
Sequence:
MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
  
Inhibitor
Name:
BDBM50609125
Synonyms:
CHEMBL1434157
Type:
Small organic molecule
Emp. Form.:
C21H20N6O3
Mol. Mass.:
404.4219
SMILES:
CCOC(=O)c1ccc(Nc2nc3nonc3nc2Nc2cccc(C)c2C)cc1
Structure:
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