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Target
Tyrosinase
Ligand
BDBM50293593
Substrate
n/a
Meas. Tech.
ChEMBL_2282156
EC50
51±n/a nM
Citation
 Li, J; Feng, L; Liu, L; Wang, F; Ouyang, L; Zhang, L; Hu, X; Wang, G Recent advances in the design and discovery of synthetic tyrosinase inhibitors. Eur J Med Chem 224:0 (2021) [PubMed] 
Target
Name:
Tyrosinase
Synonyms:
LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB
Type:
Protein
Mol. Mass.:
60388.08
Organism:
Homo sapiens (Human)
Description:
P14679
Residue:
529
Sequence:
MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGHNRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLGAAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
  
Inhibitor
Name:
BDBM50293593
Synonyms:
4-(2-aminothiazol-4-yl)benzene-1,3-diol | CHEMBL541251
Type:
Small organic molecule
Emp. Form.:
C9H8N2O2S
Mol. Mass.:
208.237
SMILES:
Nc1nc(cs1)-c1ccc(O)cc1O
Structure:
Search PDB for entries with ligand similarity: