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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50213771
Substrate
n/a
Meas. Tech.
ChEMBL_456174 (CHEMBL888184)
EC50
6340±n/a nM
Citation
 Fujieda, H; Usui, S; Suzuki, T; Nakagawa, H; Ogura, M; Makishima, M; Miyata, N Phenylpropanoic acid derivatives bearing a benzothiazole ring as PPARdelta-selective agonists. Bioorg Med Chem Lett 17:4351-7 (2007) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50213771
Synonyms:
3-(4-(2-((4-tert-butylbenzyl)(benzo[d]thiazol-2-yl)amino)ethoxy)phenyl)propanoic acid | CHEMBL247507
Type:
Small organic molecule
Emp. Form.:
C29H32N2O3S
Mol. Mass.:
488.641
SMILES:
CC(C)(C)c1ccc(CN(CCOc2ccc(CCC(O)=O)cc2)c2nc3ccccc3s2)cc1
Structure:
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