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Target
Glucagon-like peptide 1 receptor
Ligand
BDBM50221623
Substrate
n/a
Meas. Tech.
ChEMBL_457669 (CHEMBL923946)
IC50
459±n/a nM
Citation
 Teng, M; Johnson, MD; Thomas, C; Kiel, D; Lakis, JN; Kercher, T; Aytes, S; Kostrowicki, J; Bhumralkar, D; Truesdale, L; May, J; Sidelman, U; Kodra, JT; Jørgensen, AS; Olesen, PH; de Jong, JC; Madsen, P; Behrens, C; Pettersson, I; Knudsen, LB; Holst, JJ; Lau, J Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor. Bioorg Med Chem Lett 17:5472-8 (2007) [PubMed]  Article 
Target
Name:
Glucagon-like peptide 1 receptor
Synonyms:
GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1)
Type:
Enzyme
Mol. Mass.:
53035.78
Organism:
Homo sapiens (Human)
Description:
P43220
Residue:
463
Sequence:
MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
  
Inhibitor
Name:
BDBM50221623
Synonyms:
2-(4-(methylsulfonyl)benzylsulfonyl)-6,7-dichloro-3-isopropylquinoxaline | CHEMBL251760
Type:
Small organic molecule
Emp. Form.:
C19H18Cl2N2O4S2
Mol. Mass.:
473.393
SMILES:
CC(C)c1nc2cc(Cl)c(Cl)cc2nc1S(=O)(=O)Cc1ccc(cc1)S(C)(=O)=O
Structure:
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