Reaction Details Report a problem with these data
Target
Glucagon-like peptide 1 receptor
Ligand
BDBM50221642
Substrate
n/a
Meas. Tech.
ChEMBL_457667 (CHEMBL923944)
EC50
6300±n/a nM
Citation
 Teng, M; Johnson, MD; Thomas, C; Kiel, D; Lakis, JN; Kercher, T; Aytes, S; Kostrowicki, J; Bhumralkar, D; Truesdale, L; May, J; Sidelman, U; Kodra, JT; Jørgensen, AS; Olesen, PH; de Jong, JC; Madsen, P; Behrens, C; Pettersson, I; Knudsen, LB; Holst, JJ; Lau, J Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor. Bioorg Med Chem Lett 17:5472-8 (2007) [PubMed]  Article 
Target
Name:
Glucagon-like peptide 1 receptor
Synonyms:
GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1)
Type:
Enzyme
Mol. Mass.:
53035.78
Organism:
Homo sapiens (Human)
Description:
P43220
Residue:
463
Sequence:
MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
  
Inhibitor
Name:
BDBM50221642
Synonyms:
6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-amine | CHEMBL399370
Type:
Small organic molecule
Emp. Form.:
C9H7Cl2N3O2S
Mol. Mass.:
292.142
SMILES:
CS(=O)(=O)c1nc2cc(Cl)c(Cl)cc2nc1N
Structure:
Search PDB for entries with ligand similarity: