Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50275055
Substrate
n/a
Meas. Tech.
ChEMBL_495416 (CHEMBL999469)
EC50
19000±n/a nM
Citation
 Suzuki, T; Igari, S; Hirasawa, A; Hata, M; Ishiguro, M; Fujieda, H; Itoh, Y; Hirano, T; Nakagawa, H; Ogura, M; Makishima, M; Tsujimoto, G; Miyata, N Identification of G protein-coupled receptor 120-selective agonists derived from PPARgamma agonists. J Med Chem 51:7640-4 (2009) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Human
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50275055
Synonyms:
4-{4-[2-(Phenyl-2-pyridinylamino)ethoxy]phenyl}butyric Acid | CHEMBL463785
Type:
Small organic molecule
Emp. Form.:
C23H24N2O3
Mol. Mass.:
376.4483
SMILES:
OC(=O)CCCc1ccc(OCCN(c2ccccc2)c2ccccn2)cc1
Structure:
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