Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50254144
Substrate
n/a
Meas. Tech.
ChEMBL_560036 (CHEMBL1021556)
EC50
9±n/a nM
Citation
 Marx, IE; DiMauro, EF; Cheng, A; Emkey, R; Hitchcock, SA; Huang, L; Huang, MY; Human, J; Lee, JH; Li, X; Martin, MW; White, RD; Fremeau, RT; Patel, VF Discovery of alpha-amidosulfones as potent and selective agonists of CB2: synthesis, SAR, and pharmacokinetic properties. Bioorg Med Chem Lett 19:31-5 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50254144
Synonyms:
2-(4-chlorophenylsulfonyl)-2-methyl-N-(5-(5-methylthiophen-2-yl)pyridin-3-yl)propanamide | CHEMBL466821
Type:
Small organic molecule
Emp. Form.:
C20H19ClN2O3S2
Mol. Mass.:
434.959
SMILES:
Cc1ccc(s1)-c1cncc(NC(=O)C(C)(C)S(=O)(=O)c2ccc(Cl)cc2)c1
Structure:
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