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Target
Alpha-galactosidase A
Ligand
BDBM50182798
Substrate
n/a
Meas. Tech.
ChEBML_216815
IC50
40000±n/a nM
Citation
 Igarashi, Y; Ichikawa, M; Ichikawa, Y Synthesis of a new inhibitor of α-fucosidase Bioorg Med Chem Lett 6:553-558 (1996)    Article 
Target
Name:
Alpha-galactosidase A
Synonyms:
AGAL_HUMAN | Alpha-D-galactosidase A | Alpha-D-galactoside galactohydrolase | Alpha-galactosidase A | Alpha-glucosidase A (α-Gal A) | GLA | INN=Agalsidase | Melibiase
Type:
Protein
Mol. Mass.:
48760.21
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
429
Sequence:
MQLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENTMQMSLKDLL
  
Inhibitor
Name:
BDBM50182798
Synonyms:
(3R,4r,5S)-piperidine-3,4,5-triol | 1,5-Dideoxy-1,5-imino-D-xylitol | CHEMBL110830 | PIPERIDINE-3,4,5-TRIOL
Type:
Small organic molecule
Emp. Form.:
C5H11NO3
Mol. Mass.:
133.1457
SMILES:
O[C@H]1CNC[C@@H](O)[C@@H]1O |r|
Structure:
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