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Target
Vasopressin V2 receptor
Ligand
BDBM50291329
Substrate
n/a
Meas. Tech.
ChEBML_211240
IC50
9.5±n/a nM
Citation
 Moutiez, M; Lippens, G; Sergheraert, C; Tartar, A Vasopressin trisulphide: synthesis, NMR study and affinity studies with V1 and V2 subtypes receptors Bioorg Med Chem Lett 7:719-724 (1997)    Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
AVPR2 | V2R_PIG
Type:
PROTEIN
Mol. Mass.:
40556.17
Organism:
Sus scrofa
Description:
ChEMBL_214870
Residue:
370
Sequence:
MLRATTSAVPRALSWPAAPGNGSEREPLDDRDPLLARVELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATYRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGDGSGVLDCWASFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHTSLVPGPAERAGGHRGGRRAGSPREGARVSAAMAKTARMTLVIVAVYVLCWAPFFLVQLWSVWDPKAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCPRRRTPPSLRPQEESCATASSFSARDTSS
  
Inhibitor
Name:
BDBM50291329
Synonyms:
8-arginine vasopressin trisulphide | CHEMBL267405
Type:
Small organic molecule
Emp. Form.:
C46H65N15O12S3
Mol. Mass.:
1116.297
SMILES:
N[C@@H]1CSSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccc(O)cc2)NC1=O)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O
Structure:
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