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Target
Type-2 angiotensin II receptor
Ligand
BDBM50335923
Substrate
n/a
Meas. Tech.
ChEMBL_717466 (CHEMBL1670671)
Ki
480±n/a nM
Citation
 Naik, P; Murumkar, P; Giridhar, R; Yadav, MR Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorg Med Chem 18:8418-56 (2010) [PubMed]  Article 
Target
Name:
Type-2 angiotensin II receptor
Synonyms:
AGTR2 | AGTR2_HUMAN | AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Angiotensin II, central | Type-2 angiotensin II receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41201.61
Organism:
Homo sapiens (Human)
Description:
Angiotensin II, central 0 0::P50052
Residue:
363
Sequence:
MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS
  
Inhibitor
Name:
BDBM50335923
Synonyms:
1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)-2,2-difluoro-2-(2-propyl-1H-benzo[d]imidazol-1-yl)ethanol | CHEMBL1668003
Type:
Small organic molecule
Emp. Form.:
C25H22F2N6O
Mol. Mass.:
460.4786
SMILES:
CCCc1nc2ccccc2n1C(F)(F)C(O)c1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Structure:
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