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Target
Type-2 angiotensin II receptor
Ligand
BDBM50335926
Substrate
n/a
Meas. Tech.
ChEMBL_717466 (CHEMBL1670671)
IC50
50±n/a nM
Citation
 Naik, P; Murumkar, P; Giridhar, R; Yadav, MR Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorg Med Chem 18:8418-56 (2010) [PubMed]  Article 
Target
Name:
Type-2 angiotensin II receptor
Synonyms:
AGTR2 | AGTR2_HUMAN | AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Angiotensin II, central | Type-2 angiotensin II receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41201.61
Organism:
Homo sapiens (Human)
Description:
Angiotensin II, central 0 0::P50052
Residue:
363
Sequence:
MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS
  
Inhibitor
Name:
BDBM50335926
Synonyms:
5-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)-3-butyl-1-chloro-5,6-dihydroimidazo[1,5-a]pyridine-8-carboxylic acid | CHEMBL1668009
Type:
Small organic molecule
Emp. Form.:
C25H23ClN6O2
Mol. Mass.:
474.942
SMILES:
CCCCc1nc(Cl)c2C(=CCC(c3ccc(cc3)-c3ccccc3-c3nnn[nH]3)n12)C(O)=O |c:9|
Structure:
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