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Target
Type-1 angiotensin II receptor
Ligand
BDBM50335927
Substrate
n/a
Meas. Tech.
ChEMBL_717480 (CHEMBL1670685)
IC50
24±n/a nM
Citation
 Naik, P; Murumkar, P; Giridhar, R; Yadav, MR Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorg Med Chem 18:8418-56 (2010) [PubMed]  Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_CAVPO | AT1 | Angiotensin II type-1 receptor
Type:
PROTEIN
Mol. Mass.:
41004.19
Organism:
Cavia porcellus
Description:
ChEMBL_36783
Residue:
359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADICFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCVIIWLMAGLASLPAVIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFMFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKISDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSTLSTKMSTLSYRPSDNVSSSAKKPVQCFEVE
  
Inhibitor
Name:
BDBM50335927
Synonyms:
4-(2'-(1H-tetrazol-5-yl)biphenyl-4-yloxy)-2-ethyl-1,5-naphthyridine | CHEMBL1668124
Type:
Small organic molecule
Emp. Form.:
C23H18N6O
Mol. Mass.:
394.4286
SMILES:
CCc1cc(Oc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c2ncccc2n1
Structure:
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