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Target
Prostaglandin D2 receptor
Ligand
BDBM50338157
Substrate
n/a
Meas. Tech.
ChEMBL_727755 (CHEMBL1686114)
IC50
>50000±n/a nM
Citation
 Bonafoux, D; Abibi, A; Bettencourt, B; Burchat, A; Ericsson, A; Harris, CM; Kebede, T; Morytko, M; McPherson, M; Wallace, G; Wu, X Thienopyrrole acetic acids as antagonists of the CRTH2 receptor. Bioorg Med Chem Lett 21:1861-4 (2011) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50338157
Synonyms:
2-(6-(4-(N-cyclohexyl-N-methylsulfamoyl)benzyl)-5-methyl-6H-thieno[2,3-b]pyrrol-4-yl)acetic acid | CHEMBL1684726
Type:
Small organic molecule
Emp. Form.:
C23H28N2O4S2
Mol. Mass.:
460.609
SMILES:
CN(C1CCCCC1)S(=O)(=O)c1ccc(Cn2c(C)c(CC(O)=O)c3ccsc23)cc1
Structure:
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