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Target
Low molecular weight protein-tyrosine phosphatase A
Ligand
BDBM50345500
Substrate
n/a
Meas. Tech.
ChEMBL_751030 (CHEMBL1786815)
Ki
22500±n/a nM
Citation
 Chandra, K; Dutta, D; Mitra, A; Das, AK; Basak, A Design, synthesis and inhibition activity of a novel cyclic enediyne amino acid conjugates against MPtpA. Bioorg Med Chem 19:3274-9 (2011) [PubMed]  Article 
Target
Name:
Low molecular weight protein-tyrosine phosphatase A
Synonyms:
PTPA_MYCTU | PTPase | Probable low molecular weight protein-tyrosine-phosphatase | Protein Tyrosine Phosphatase PTPA | mptpA | ptpA
Type:
Hydrolase
Mol. Mass.:
17891.84
Organism:
Mycobacterium tuberculosis
Description:
n/a
Residue:
163
Sequence:
MSDPLHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWHVGSCADERAAGVLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQLGVEAARVRMLRSFDPRSGTHALDVEDPYYGDHSDFEEVFAVIESALPGLHDWVDERLARNGPS
  
Inhibitor
Name:
BDBM50345500
Synonyms:
6-oxo-1,2,9,10-tetradehydro-3,4,5,6-tetrahydro-5-benzazacyclododecine-7-carboxylic acid | CHEMBL1784316
Type:
Small organic molecule
Emp. Form.:
C16H11NO3
Mol. Mass.:
265.2634
SMILES:
OC(=O)C1=C/C#Cc2ccccc2C#CCCNC\1=O |t:3|
Structure:
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