Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM50357394
Substrate
n/a
Meas. Tech.
ChEMBL_787850 (CHEMBL1918616)
IC50
>100000±n/a nM
Citation
 Liu, D; Kong, G; Chen, QC; Wang, G; Li, J; Xu, Y; lin, T; Tian, Y; Zhang, X; Yao, X; Feng, G; Lu, Z; Chen, H Fatty acids as natural specific inhibitors of the proto-oncogenic protein Shp2. Bioorg Med Chem Lett 21:6833-7 (2011) [PubMed]  Article 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM50357394
Synonyms:
CHEMBL1917283
Type:
Small organic molecule
Emp. Form.:
C21H40O9
Mol. Mass.:
436.5369
SMILES:
CCCCCCCCCCCC(=O)OCC(O)CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: