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Target
Mu-type opioid receptor
Ligand
BDBM50016086
Substrate
n/a
Meas. Tech.
ChEBML_145304
Ki
31±n/a nM
Citation
 Archer, S; Seyed-Mozaffari, A; Ward, S; Kosterlitz, HW; Paterson, SJ; McKnight, AT; Corbett, AD 10-Ketonaltrexone and 10-ketooxymorphone. J Med Chem 28:974-6 (1985) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50016086
Synonyms:
4-cyclopropylmethyl-10,17-dihydroxy-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-triene-6,14-dione(Ketonaltrexone) | CHEMBL366520
Type:
Small organic molecule
Emp. Form.:
C20H21NO5
Mol. Mass.:
355.3844
SMILES:
Oc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)C(N(CC5CC5)CCC314)C2=O |TLB:14:13:5.24.4:16.22.21,6:5:13:16.22.21,THB:25:24:13:16.22.21|
Structure:
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