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Target
Mu-type opioid receptor
Ligand
BDBM50021779
Substrate
n/a
Meas. Tech.
ChEBML_149000
Ki
84±n/a nM
Citation
 Awaya, H; May, EL; Aceto, MD; Harris, LS; Silverton, JV; Rice, KC; Mattson, MV; Jacobson, AE Hexahydro-1H-1-pyrindines from acid rearrangement of 9-alkylidene-5-(m-methoxyphenyl)-2-methylmorphans. A new structural type of narcotic antagonists. J Med Chem 30:947-50 (1987) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44503.11
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:
398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50021779
Synonyms:
3-(4a-Ethyl-1-methyl-2,4a,5,6,7,7a-hexahydro-1H-[1]pyrindin-4-yl)-phenol | CHEMBL172961
Type:
Small organic molecule
Emp. Form.:
C17H23NO
Mol. Mass.:
257.3706
SMILES:
CC[C@]12CCC[C@H]1N(C)CC=C2c1cccc(O)c1 |c:11|
Structure:
Search PDB for entries with ligand similarity: